Article Archives - Page 2 of 4

Blog posts

Dynamic single-molecule analysis reveals non-linear stiffening of mitotic chromosomes

In a recent study performed by Vrije Universiteit Amsterdam and the University of Copenhagen, researchers used LUMICKS’ u-Flux™ laminar flow microfluidics system together with optical tweezers and fluorescence microscopy – features combined in LUMICKS’ C-Trap® – to shed light on the structural organization of mitotic chromosomes. When preparing to undergo…

Chenlu Yu17 June 2022

Blog posts

The Scientist Magazine features z-Movi^®;

We couldn't have put the essence of our z-Movi®; in better words than the author of this article in The Scientist: "Just as music pulls some folks to the dance floor while others remain stuck to their chairs, sound can now be used to pull some cells loose from their substrate while other cells…

j.yeh25 January 2019

Blog posts

z-Movi^® featured in Science

Our latest product, the z-Movi®;, has been featured in the latest issue of the journal Science! The z-Movi uses acoustic force manipulation to query the interaction strengths of cells with their cognate binding partners. It is based on a lab-on-a-chip assay that allows the assessment of thousands of cell-cell and cell-ligand interactions…

j.yeh5 December 2018

Blog posts

LUMICKS Featured in Cambridge Independent

This week’s issue of Cambridge Independent featured an article about our partnership with AstraZeneca and the University of Cambridge! We are proud to see the field of dynamic single-molecule analysis reaching a new milestone once again. This brings us closer to our goal: improving human health by providing unparalleled insight…

Jerom Langeveld23 July 2018

Measure Cell Mechanics with Acoustic Force Spectroscopy

Blog posts

Novel Method for Single-Cell Mechanical Probing using LUMICKS’ AFS™ System

The article ‘Probing cellular mechanics with Acoustic Force Spectroscopy’ has recently been published in the journal Molecular Biology of the Cell. Congratulations to all the authors on their inspiring research! Undergoing deformations plays a vital role in the function of Red Blood Cells (RBCs) and could be used as a biomarker,…

Jerom Langeveld10 July 2018

Blog posts

Novel Insights on the Mechanical Properties of IFs using LUMICKS’ Technology

The journal Science Advances has recently published the paper ‘Viscoelastic properties of vimentin originate from nonequilibrium conformational changes’. We would like to congratulate Prof. Dr. Sarah Köster and all co-authors for their great work on intermediate filaments (IFs)! IFs are one of the filament systems which constitute the cytoskeleton of…

Jerom Langeveld18 June 2018

Blog posts

Method to Quantify Local Force Distribution within Biomolecular Systems

The journal Nano Letters has recently published the article “Quantifying Local Molecular Tension Using Intercalated DNA Fluorescence”. We would like to congratulate all the authors! By using optical tweezers coupled with fluorescence microscopy, Dr. King et al. (2018) studied the ability of cyanine intercalator dyes to quantify the molecular tension…

Jerom Langeveld25 April 2018

optical tweezers dna repair force extension manipulation visualization RAD51 Recombination

Blog posts

Investigation of the Interaction of RAD51 with ssDNA Using CTFM and X-ray Crystallography

Recently, the paper “Two distinct conformational states define the interaction of human RAD51-ATP with single-stranded DNA" has been published in The EMBO Journal. Congratulations to Dr. Ineke Brouwer and all co-authors! Brouwer et al. combined Correlative Optical Tweezers-Fluorescence Microscopy (CTFM) with X-ray crystallography to investigate the function of human RAD51…

Jerom Langeveld20 March 2018

Blog posts

LUMICKS co-founding Professors G. Wuite & E. Peterman in the media after winning the NWO Physics Valorisation Prize 2017

After being awarded the NWO Physics Valorisation Prize 2017 for the valorization of their single-molecule research, Prof. Gijs Wuite and Prof. Erwin Peterman are featured in an article published in VU Magazine and an interview on a famous Dutch radio station (both in Dutch). The article showcases who these top biophysicists are,…

Jerom Langeveld27 February 2018

strand-displacement polymerization investigated with u-Flux microfluidics microfluidics laminar flow cell

Blog posts

Strand-Displacement Polymerization by Reverse Transcriptase Investigated using LUMICKS’ u-Flux™

The journal Nucleic Acids Research has recently published the paper "Pausing kinetics dominates strand-displacement polymerization by reverse transcriptase". We would like to congratulate the authors! Malik et al. (2017) used optical tweezers and, among other technologies, microfluidics to study the enzymatic activity of the murine leukemia Virus reverse transcriptase (RT). RT catalyzes the formation of an integration-competent double-stranded DNA…

Jerom Langeveld26 September 2017

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Article

Dynamic single-molecule analysis reveals non-linear stiffening of mitotic chromosomes

The Scientist Magazine features z-Movi^®;

z-Movi^® featured in Science

LUMICKS Featured in Cambridge Independent

Novel Method for Single-Cell Mechanical Probing using LUMICKS’ AFS™ System

Novel Insights on the Mechanical Properties of IFs using LUMICKS’ Technology

Method to Quantify Local Force Distribution within Biomolecular Systems

Investigation of the Interaction of RAD51 with ssDNA Using CTFM and X-ray Crystallography

LUMICKS co-founding Professors G. Wuite & E. Peterman in the media after winning the NWO Physics Valorisation Prize 2017

Strand-Displacement Polymerization by Reverse Transcriptase Investigated using LUMICKS’ u-Flux™

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