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DNA-protein interactions (DPI) Archives - LUMICKS

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C-Trap® installed at Emory University in AtlantaUncategorised

C-Trap® installed at Emory University in Atlanta

We are happy to announce the installation of a new C-Trap® system with correlated optical tweezers and three-color confocal imaging functionality at Emory University in Atlanta, Georgia. The installed instrument, which is managed by the research group of Prof. Laura Finzi and Dr. David Dunlap, will be used by several…
Santiago Gisler
18 November 2020
Uncategorised

New insights into the initiation of nucleotide excision repair found using C-Trap®

A recent publication in PNAS shows how the catalytically inactive alkyltransferase-like protein (ATL) scans and recognizes detrimental DNA alkylation lesions. The C-Trap® with correlated optical tweezers and confocal microscopy enabled researchers to investigate how ATL interacts with DNA to identify alkyl lesions and interact with associated repair proteins. The findings…
Santiago Gisler
30 April 2020
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