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C-Trap® installed at Imperial College LondonBlog posts

C-Trap™ installed at Imperial College London

Recently, LUMICKS successfully installed a new C-Trap® optical tweezers-fluorescence microscopy system in the lab of Professor David Rueda at the Imperial College London, England, whose lab also features an AFS™ system for high throughput measurements. The group of Prof. Rueda develops and uses quantitative single-molecule approaches to investigate mechanisms underlying complex biological processes. These…
Jerom Langeveld
18 December 2017
High-Throughput Label-free Cell Interaction StudiesBlog posts

High-Throughput Label-free Cell Interaction Studies

At the ASCB | EMBO 2017 meeting, we introduced z-Movi®, a new platform for cell interaction studies. This new method enables direct and label-free screening and sorting of thousands of cells based on their interaction with cell or protein targets. z-Movi® is a breakthrough technology for research and development of personalized therapies, including immunotherapy. It is…
Jerom Langeveld
5 December 2017
AFS™ installed at Johns Hopkins UniversityBlog posts

AFS™ installed at Johns Hopkins University

LUMICKS is happy to announce the installation of an AFS™ Stand-alone system at Johns Hopkins University. JHU is now the home of both a C-Trap® and AFS! The labs of Professor Taekjip Ha and Assistant Professor Christian Kaiser will share the instrument. Prof. Ha's group studies complex biological mechanisms, by pushing the limits of single-molecule detection methods. They…
Jerom Langeveld
1 December 2017
AFS USTC Prof. Luo installedBlog posts

AFS™ Installed at University of Science and Technology of China

A new AFS™ system was recently installed in the lab of Professor Tianzhi Luo at the University of Science and Technology of China, Hefei. The research interests of the group of Prof. Luo lie in, among other topics, mechanobiology and cell mechanics. They will combine the AFS Module with their own inverted optical microscope. This allows the…
Jerom Langeveld
29 November 2017
m-Trap Optical TweezersBlog posts

Introducing m-Trap® Optical Tweezers

Today, we release the m-Trap®. Watch the launch video! The m-Trap is the first dedicated optical tweezers platform specifically designed to enable scientists to manipulate and measure at the single-molecule level with ultra-high resolution, stability & throughput, at an unprecedented price. We hope that introducing this instrument will bring us closer to the LUMICKS dream of truly unlocking single-molecule analysis.
Jerom Langeveld
23 November 2017
C-Trap installation University of ZurichBlog posts

C-Trap® installed at University of Zürich

Recently, LUMICKS successfully installed a new C-Trap® Optical Tweezers system, with a quadruple trap configuration, in the lab of Professor Ben Schuler at the University of Zürich, Switzerland. The group of Prof. Schuler uses single-molecule spectroscopy with the aim to understand protein folding, disorder and dynamics. The C-Trap® will be the group's first experience…
Jerom Langeveld
3 November 2017
Single-Molecule-Workshop-102017HQ-Lecture-by-Gijsje-KoenderinkBlog posts

Single-Molecule Workshops at LUMICKS’ headquarters

On October 23-25, LUMICKS organized two fruitful workshops on Optical Tweezers-Fluorescence Microscopy & Acoustic Force Spectroscopy at our headquarters in Amsterdam. The practical hands-on workshops included demonstrations on the latest developments and applications of the C-Trap® and  AFS™, given by our application scientists. In addition, the participants performed state-of-the-art single-molecule experiments and…
Jerom Langeveld
31 October 2017
correlative-optical-tweezers-fluorescence-workshopBlog posts

Optical Tweezers-Fluorescence Microscopy Workshops at the Rockefeller University

On October 10-12, the lab of Prof. Shixin Liu at the Rockefeller University in New York hosted two successful workshops on Optical Tweezers-Fluorescence Microscopy, organized by LUMICKS. During the practical hands-on workshops, the participants learned about the latest developments and applications of the C-Trap®. Furthermore, together with our application scientists, they conducted…
Jerom Langeveld
20 October 2017
DNA BreathingBlog posts

DNA Breathing Application Note Now Online

DNA breathing, also known as fraying, describes the spontaneous local conformational transitions occurring within double-stranded DNA (dsDNA). Due to the transient and spontaneous nature of this process, the study of real-time DNA breathing transitions at the single-molecule level requires the use of highly sensitive experimentation technologies. Using LUMICKS’ high-resolution optical tweezers, small and transient DNA…
Jerom Langeveld
28 September 2017
strand-displacement polymerization investigated with u-Flux microfluidics microfluidics laminar flow cellBlog posts

Strand-Displacement Polymerization by Reverse Transcriptase Investigated using LUMICKS’ u-Flux™

The journal Nucleic Acids Research has recently published the paper "Pausing kinetics dominates strand-displacement polymerization by reverse transcriptase". We would like to congratulate the authors! Malik et al. (2017) used optical tweezers and, among other technologies, microfluidics to study the enzymatic activity of the murine leukemia Virus reverse transcriptase (RT). RT catalyzes the formation of an integration-competent double-stranded DNA…
Jerom Langeveld
26 September 2017
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