DNA replication Archives

Blog posts

The C-Trap uncovers new insights into the mechanisms for ATP-dependent chromatin remodeling

PICH (Plk1-interacting checkpoint helicase) belongs to the SNF2 family of ATP-dependent chromatin remodelers. However, what makes PICH unique is that it lacks a nucleotide-binding domain despite having a great affinity for bare DNA. Because of this molecular structure, it has been hypothesized that the binding of PICH to chromatinized bridges…

Chenlu Yu13 June 2023

Blog posts

100th study using the C-Trap^® provides crucial insights into how the Smc5/6 complex stabilizes certain DNA structures

A recent study published in Nature Communications led by Shixin Liu from The Rockefeller University, New York, demonstrates how the C-Trap® can be used to directly visualize and observe molecular mechanisms in action, leading to better and faster insights into critical molecular processes. This study marks an important milestone for LUMICKS,…

Chenlu Yu28 March 2023

Blog posts

Three C-Trap^® systems installed in the US East Coast

We are excited to share that three more institutes on the US East Coast are now equipped with a C-Trap® Optical Tweezers – Fluorescence Microscope! The three new instruments are now housed at a new core facility at MSKCC, at the NanoSystems Laboratory at the OSU, and at the UPMC-Hillman Cancer…

j.yeh17 May 2021

C-Trap® installed at Imperial College London, UK

Blog posts

LUMICKS DSM technologies installed in South East UK

We are happy to share our news about the most recent C-Trap® and m-Trap® installations in the UK! We’ll start with the recently installed C-Trap system at the MRC-London Institute of Medical Sciences, Imperial College London that is used by the cell biologists and biochemists at the group of Prof. Luis…

Adrià Ferragut4 May 2021

Blog posts

New study resolves helicase dynamics and interactions during DNA replication using C-Trap^®

Researchers from Rockefeller University used a C-Trap® optical tweezers – fluorescence microscopy system to observe the behavior of the main component of the replisome – the eukaryotic CMG helicase – during DNA replication. The study offers exciting new insights into the interactions, processes, and structural plasticity associated with CMG during…

j.yeh26 July 2019

Join our newsletter

First Name

Last Name

E-mail address *

Country

Get exclusive news on the latest publications, product developments, events and breakthrough science.

Application of interest *

Dynamic single-molecule analysis

Cell avidity analysis

By submitting the form you agree to LUMICKS' privacy policy. You can revoke your consent at any time.

If you are human, leave this field blank.

Cookie	Duration	Description
Boxzilla	3 days	This cookie remembers if you have already closed a modal to make sure we don't show you the same information twice.
cookielawinfo-checkbox-advertisement	1 year	Set by the GDPR Cookie Consent plugin, this cookie is used to record the user consent for the cookies in the "Advertisement" category .
cookielawinfo-checkbox-analytics	11 months	This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Analytics".
cookielawinfo-checkbox-functional	11 months	The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional".
cookielawinfo-checkbox-necessary	11 months	This cookie is set by GDPR Cookie Consent plugin. The cookies is used to store the user consent for the cookies in the category "Necessary".
cookielawinfo-checkbox-others	11 months	This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Other.
cookielawinfo-checkbox-performance	11 months	This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Performance".
CookieLawInfoConsent	1 year	Records the default button state of the corresponding category & the status of CCPA. It works only in coordination with the primary cookie.
viewed_cookie_policy	11 months	The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data.

Cookie	Duration	Description
_ga	2 years	The _ga cookie, installed by Google Analytics, calculates visitor, session and campaign data and also keeps track of site usage for the site's analytics report. The cookie stores information anonymously and assigns a randomly generated number to recognize unique visitors.
_gat_gtag_UA_57399829_1	1 minute	Set by Google to distinguish users.
_gcl_au	3 months	Provided by Google Tag Manager to experiment advertisement efficiency of websites using their services.
_gid	1 day	Installed by Google Analytics, _gid cookie stores information on how visitors use a website, while also creating an analytics report of the website's performance. Some of the data that are collected include the number of visitors, their source, and the pages they visit anonymously.
Clarity		Clarity is a user behavior analytics tool that helps you understand how users are interacting with our website through session replays and heatmaps.
Google Analytics Universal	1 minute	A variation of the _gat cookie set by Google Analytics and Google Tag Manager to allow website owners to track visitor behaviour and measure site performance. The pattern element in the name contains the unique identity number of the account or website it relates to.
pardot	past	The pardot cookie is set while the visitor is logged in as a Pardot user. The cookie indicates an active session and is not used for tracking.
Pardot visitor	1 year	No description
Pardot visitor hashed	1 year	The Pardot cookie to link visitors to prospects

Cookie	Duration	Description
Cience		Tracking performance of Cience ads
Linkedin Insight		The LinkedIn Insight tag helps us keep track of conversions and traffic coming from the LinkedIn platform.
test_cookie	15 minutes	The test_cookie is set by doubleclick.net and is used to determine if the user's browser supports cookies.

DNA replication

The C-Trap uncovers new insights into the mechanisms for ATP-dependent chromatin remodeling

100th study using the C-Trap^® provides crucial insights into how the Smc5/6 complex stabilizes certain DNA structures

Three C-Trap^® systems installed in the US East Coast

LUMICKS DSM technologies installed in South East UK

New study resolves helicase dynamics and interactions during DNA replication using C-Trap^®

Recent Posts

Applications

Products

About LUMICKS

For pricing, reach out to your application scientist or account manager

Fill in our contact form, we will reach out to you!

Join our newsletter

Download our webinar recording:

Download our Cell Therapy (CAR-T, TCR, NK) applications deck

DNA replication

The C-Trap uncovers new insights into the mechanisms for ATP-dependent chromatin remodeling

100th study using the C-Trap® provides crucial insights into how the Smc5/6 complex stabilizes certain DNA structures

Three C-Trap® systems installed in the US East Coast

LUMICKS DSM technologies installed in South East UK

New study resolves helicase dynamics and interactions during DNA replication using C-Trap®

Recent Posts

Tags

Applications

Products

About LUMICKS

For pricing, reach out to your application scientist or account manager

Fill in our contact form, we will reach out to you!

Join our newsletter

Download our webinar recording:

Download our Cell Therapy (CAR-T, TCR, NK) applications deck

Accept cookies for the best website experience

100th study using the C-Trap^® provides crucial insights into how the Smc5/6 complex stabilizes certain DNA structures

Three C-Trap^® systems installed in the US East Coast

New study resolves helicase dynamics and interactions during DNA replication using C-Trap^®