New product line C-Trap ‘Edge’ adds important capabilities relevant for surface assays, which are of increasing importance in biophysical and biology research.
j.yeh18 February 2022
In a first-of-its-kind study from Leiden University, Evers et al. have provided insights into the mechanical properties of monocytes – cells crucial in the fight against infection. By combining two of LUMICKS’ single-cell force spectroscopy approaches, C-Trap® optical tweezers and acoustic force spectroscopy (AFS), they were able to determine that…
Chenlu Yu16 February 2022
C-Trap® technology was used in new research designed to understand the function of a key protein involved in DSB) repair. DSB repair is fundamental in maintaining the genome integrity and when compromised can lead to cancer predisposition.
j.yeh15 February 2022
We are thrilled to announce the recent C-Trap® installation at École Normale Supérieure Lyon, now the first establishment in France to acquire a C-Trap, where it will be utilized by an astonishing 8 teams across 3 departments! The Physics Department (LPENSL), Cell Biology Department (LBMC), and Plant Biology Department (RDP)…
Adrià Ferragut28 January 2022
The C-Trap will support the research of Prof. Michael O’Donnell to investigate the mechanisms of DNA replication. Between O’Donnell and his collaborator Prof Shixin Liu, Rockefeller University will use the C-Trap to unveil the mechanisms of many types of enzymes, such as multi-protein DNA replicating machines of bacteria and eukaryotes.
j.yeh11 January 2022
A recent paper published in Nature by the group of Dr. Simon Boulton from the Francis Crick Institute enlightens the role played by the helicase HELQ in the context of DNA repair. The researchers took advantage of the combination of microfluidics, optical tweezers, and fluorescence microscopy of the C-Trap® to…
j.yeh23 December 2021
A new Nature Communications article sheds light into the mechanisms that govern programmed ribosomal frameshifting (PRF) in SARS-CoV-2 virus, as demonstrated by C-Trap experiments.
j.yeh13 December 2021
A recent work published in eLife by Francisco de Asis Balaguer et al. shed light on the interaction of ParB with DNA, the consequent DNA condensation, and the role of cytidine triphosphate (CTP) in this process – at a single-molecule level. Using the C-Trap® the researchers investigated the role of…
j.yeh30 November 2021
The Technical University of Munich, Germany, is now the home of two C-Trap® Optical Tweezers – Fluorescence Microscopes. With this second installation, the renowned lab of Prof. Matthias Rief is taking their dynamic single-molecule research to the next level. Prof. Rief is a pioneer in studying processes involved in protein…
j.yeh24 November 2021
A recent study by Szu‐Ning Lin et al. for the first time provided direct information on the dynamics of the interaction between HU and DNA and how this interaction is influenced by ionic conditions and DNA conformation.
j.yeh9 November 2021
