“With the help of LUMICKS, my student started using this equipment after about 30 minutes of training [and] was quickly able to generate lots of data from it. I feel like this is going to be a very exciting tool in my lab that can help us to answer many important questions we have.”

Prof. Hang ShiPrincipal Scientist at the School of Life Sciences at Tsinghua University

“We will be able to use microfluidics to study function-related dynamics of a single molecule under different experimental conditions. Combined with the power of having a simultaneous mechanical and fluorescent readout, we will be able to uncover previously unexplored details of the conformational cycles of our model proteins.”

Dr. Katarzyna TychPrincipal investigator at the University of Groningen

“We use the C-Trap to directly measure the multidimensional effects of mechanical forces in protein (un)folding, enabled by the combination of single-molecule fluorescence with optical tweezers. These findings provide insights into the mechanisms by which chaperones act to control protein conformations and folding to the native state.”

Prof. Sander TansGroup Leader at the FOM Institute AMOLF

“With such quantitative measurements, we hope to contribute to the understanding of biological processes in which membrane remodeling plays a central role.”

Dr. Raya SorkinSenior Lecturer at Tel Aviv University

“The user-friendly software combined with the high throughput experimental workflow and the dedicated training we received from LUMICKS, has fully equipped us to perform state-of-the-art single-molecule force spectroscopy experiments in no time.”

Prof. Ben SchularProfessor of Molecular Biophysics, University of Zurich

“With the C-Trap, our group can expand our capabilities to investigate nucleic acid mechanics and DNA-protein interactions in novel ways, [we] can now locate fluorescently-labeled proteins on DNA substrates and follow their dynamics in real-time.”

Prof. Fernando Moreno-HerreroPrincipal Investigator at the Centro Nacional de Biotecnología

“The m-Trap and Bluelake software have allowed my lab to get started immediately on experiments due to a user-friendly interface and technical support from LUMICKS. We are excited to use this technology to decipher how the nucleus senses and uses mechanical force.”

Dr. Adrian OlivaresAssistant Professor at Vanderbilt University

“The correlation of force traces with fluorescence observation provides very powerful insights for our research. The team has been fighting over system time!”

Prof. Stephen GrillDirector and Research Group Leader at the MPI-CBG

“Through Harbor, I can help the community with ready-to-go scripts, while getting credit for the work I've done through extra citations.”

John WattersGraduate Fellow at the lab of Shixin Liu, Rockefeller University

“By allowing us to manipulate the topology of DNA molecules while simultaneously imaging the DNA and DNA binding proteins with high spatial and temporal resolution, the C-Trap will open up exciting new avenues of research in the Neuman lab.”

Dr. Kier NeumanGroup Leader at the NIH - National Heart, Lung, and Blood Institute

“C-Trap is a unique and powerful tool that helped us unravel precise molecular mechanisms on how cohesin tethers chromatids. By using the shared instrument located at the Imperial College London together with our collaborators, we were able to perform valuable measurements and build the data presented in our publication* in a few weeks of measurements.”

Prof. Luis AragónProfessor at the London Institute of Medical Sciences

“We believe that the great force resolution and time stability of the m-Trap will be precious assets for us to depict crucial information about the mechanics and work processes of biological and artificial molecular machines", stated Dr. Damien Sluysmans, a researcher in the Duwez group.”

Prof. Anne-Sophie DuwezProfessor and group leader at the University of Liege

“The new system will bring more collaborators and new research ideas from different life science groups, who are interested in optical and single-molecule biomanipulation. Having the C-Trap together with optical expertise in the group will serve the local research environment with state-of-the-art equipment and highly trained experts.”

Prof. Poul Martin BendixProfessor at the University of Copenhagen

“We are extremely pleased to have received the generous support of the BBSRC (grant ref.MR/S021248/1) that enabled us to provide the University of Cambridge with a state-of-the-art single-molecule instrument that was not previously available to the Cambridge community of researchers. We are looking forward to the many novel insights that the C-trap will provide.”

Prof. Lucas PellegriniProfessor at the University of Cambridge, Department of Biochemistry

“The combination of force and single-molecule fluorescence, in an easy-to-use system will accelerate experiments that take days to just take minutes. Making complex tools easier to use, will make ours and the scientific community’s science move faster.”

Dr. Neil KadReader in Molecular Biophysics at the University of Kent

“Just as impressive as the craftsmanship of the instrument is the professional and timely customer support that LUMICKS has provided us on a regular basis over the past years. The relationship between the LUMICKS team and my team is more of a collaborative nature, which is unique and what I find most enjoyable.”

Dr. Shixin LiuAssistant Professor at Rockefeller University and head of the Laboratory of Nanoscale Biophysics and Biochemistry

“The z-Movi is the first high throughput tool I have seen to reliably measure cell:cell avidity, allowing us to dissect the temporal nature of the formation of NK cell:tumor cell synapse as well as the critical components required for synapse stability and NK cell triggering...”

Prof. Mark LowdellCSO at INmune Bio

“We expect to gain greater insight into the mechanism of CAR mediated tumor cell recognition and into the selection of the most potent CAR for clinical application...”

Dr. Hinrich AbkenChair for Genetic Immunotherapy at Regensburg University

“Using this technology of the z-Movi^® Cell Avidity Analyzer, we can identify the results that we could be able to see in vivo, which could not be predicted with other strategies in vitro.”

Prof. Carlos Fernandez LarreaUniversity Hospital Barcelona

“The z-Movi^® provided an essential piece of evidence in our investigations, giving us critical insight into how these engineered cells work and what is ultimately responsible for their changes in behavior with this new dual-targeting strategy...”

Dr. Maria ThemeliGroup Leader of Hematology Department at Amsterdam UMC Cancer Center Amsterdam

“The z-Movi system has enabled us to rapidly rank CAR T-cells containing distinct targeting moieties in terms of their avidity for target cells. Since this relies on CAR T-cell to target cell interaction rather than more artificial alternatives, it allows us to pick the “Goldilocks binders” that achieve superior performance.”

Prof. John MaherCSO at Leucid Bio