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C-Trap

Blog posts

New insights into Cas9 off-target activity

The paper “DNA stretching induces Cas9 off-target binding and cleavage” was just published in Nature Structural and Molecular Biology. Congratulations to all the authors! In this paper, scientists at the MRC London Institute of Medical Sciences and AstraZeneca studied how CRISPR-Cas9 differentiates between on-targets and off-targets. They used the C-Trap®…
j.yeh
8 March 2019
C-Trap m-Trap 2019 Brochure CoversBlog posts

Step into the unresolved with the Surface Assay Toolkit

During BPS19, we introduced the Surface Assay Toolkit! A unique assortment of new features that enable scientists to investigate the cytoskeleton from a whole new dynamic perspective. The Surface Assay Toolkit brings together the C-Trap™ and m-Trap™ optical tweezers with:  Label-free surface imaging using IRM;  Rapid fluorescent imaging in solution using Widefield;  Fluorescence surface imaging using TIRF;  High throughput experimental workflow at the surface. Download the 2019…
j.yeh
7 March 2019
C-Trap Installation at UC MercedBlog posts

C-Trap™ installed at UC Merced

A C-Trap™, optical tweezers coupled with fluorescence microscopy, has been successfully installed at the University of California, Merced. The system is shared by the research groups of Prof. Eva de Alba and Prof. Victor Muñoz. Their labs focus on the study of proteins, which are involved in almost all cellular processes. This makes the…
Jerom Langeveld
18 February 2019
Blog posts

C-Trap installed at TU Delft

We are thrilled about the recent C-Trap® installation in the Department of Bionanoscience at the TU Delft, one of the leading universities in The Netherlands! The groups of Prof. Nynke Dekker and Prof. Marileen Dogterom will use the C-Trap to study the dynamic aspects of DNA replication and cytoskeleton-based processes,…
Jerom Langeveld
13 December 2018
phase separation IDP researchBlog posts

New C-Trap™ Installed at the University at Buffalo

LUMICKS successfully installed a C-Trap® optical tweezers–fluorescence microscopy system in the lab of Assistant Professor Priya Banerjee at the University at Buffalo. The group of Dr. Banerjee will use the C-Trap to investigate the structural dynamics and phase behavior of intrinsically disordered proteins (IDPs). IDPs are characterized by conformational plasticity and structural heterogeneity,…
Jerom Langeveld
17 October 2018
Single-Molecule Workshop at the University of CambridgeBlog posts

Single-Molecule Workshop at the University of Cambridge

An engaging single-molecule workshop organized by LUMICKS took place at the University of Cambridge. During the workshop, the participants performed state-of-the-art experiments to examine DNA-protein interactions and DNA mechanics in real-time and at the single-molecule level, using the C-Trap® optical tweezers - fluorescence microscopy system. Next to the practical sessions, Matt Newton, a researcher from…
Jerom Langeveld
2 October 2018
Leiden c-trap installation Alireza Mashaghi LabBlog posts

C-Trap™ installed at Leiden University

LUMICKS is happy to announce that a new C-Trap™ optical tweezers is now housed in the lab of Dr. Alireza Mashaghi at Leiden University, the Netherlands. Dr. Mashaghi’s group will use the C-Trap to perform single-molecule experiments and investigate molecular folding processes. In particular, the group aims to understand how chaperones reshape…
2 October 2018
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