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m-Trap installation at Vanderbilt UniversitBlog posts

m-Trap™ installed at Vanderbilt University

The lab of Assistant Professor Adrian Olivares (Vanderbilt University, Nashville, TN) is now equipped with a m-Trap® Optical Tweezers system. "The m-Trap and Bluelake software have allowed my lab to get started immediately on experiments due to a user-friendly interface and technical support from LUMICKS. We are excited to use this technology to decipher…
j.yeh
18 June 2019
Blog posts

Two papers give new insights on protein droplets using LUMICKS’ C-Trap™

Two new papers published at Physical Review Letters and Nature Communications give new insights on protein droplets. Congratulations to all the authors! Jawerth et al. developed a method to investigate the frequency-dependent rheology and surface tension of protein droplets. They used the C-Trap™ optical tweezers – fluorescence microscope to trap…
j.yeh
31 May 2019
C-Trap® SR installed at the National Institutes of Health (NIH)Blog posts

C-Trap® SR installed at the National Institutes of Health (NIH)

A new C-Trap® SR was installed at the National Institutes of Health, Maryland, USA, in the labs of Prof. Antonina Roll-Mecak and Prof. Keir Neuman. The LUMICKS optical tweezers-STED nanoscopy system allows the user to visualize molecular interactions with super-resolution microscopy. The highly interdisciplinary group of Prof. Roll-Mecak works on unraveling the chemical and genetic complexity of the microtubule cytoskeleton, or "the tubulin code". The…
Jerom Langeveld
14 May 2019
Single-Molecule Workshop at ShanghaiTechBlog posts

Dynamic Single-Molecule Workshop at the ShanghaiTech University

The first dynamic single-molecule workshop of the year just came to an end! Last week, 16 participants got to experience the C-Trap® Optical Tweezers – Fluorescence Microscope to investigate DNA mechanics and do experiments using their own samples. Additionally, the workshop included lectures from Prof. Bo Sun, during which he discussed his…
j.yeh
26 April 2019
C-Trap® SR installed at Northeastern UniversityBlog posts

C-Trap™ SR installed at Northeastern University

We are happy to have installed a C-Trap® SR, our optical tweezers-STED nanoscope, in shared lab space for an interdisciplinary group led by Prof. Mark Williams at Northeastern University, in Massachusetts, USA. The lab of Prof. Williams is highly regarded as one of the leaders of single-molecule analysis, making us even more proud of this installation. The lab focuses…
j.yeh
16 April 2019
C-Trap installation at Sun Yat-sen University, ChinaBlog posts

C-Trap™ installed at Sun Yat-sen University, China

School of Physics at the Sun Yat-sen University, China, is now equipped with a C-Trap™ Optical Tweezers-Fluorescence Microscope. This advanced instrument is believed to be able to boost up a variety of exciting researches in SYSU, such as DNA/RNA mechanics and protein-DNA or -RNA interactions during DNA replication, transcription, and repair that Prof.…
j.yeh
8 April 2019
AFS installation at GottingenBlog posts

AFS™ installed at University of Göttingen

An AFS™ system was installed in the lab of Professor Andreas Janshoff at the Department of Biophysical Chemistry at the University of Göttingen, Germany. Together with the team of Professor Claudia Steinem (Institute for Organic and Biomolecular Chemistry), the Janshoff group will use it to investigate the properties of and…
j.yeh
4 April 2019
C-Trap installation at B CUBE TU DresdenBlog posts

Second C-Trap™ installed in Dresden, Germany

The city of Dresden, Germany, is now the home of two C-Trap® systems! The latest installation took place at the Center for Molecular and Cellular Bioengineering at TU Dresden, where the instrument became part of the Joint Technology Platform. Being operated in the "Molecular Imaging and Manipulation" facility, the system will be available to multiple…
j.yeh
26 March 2019
AFS installation at Victor Chang Cardiac Research Institute, AustraliaBlog posts

First AFS™ installed in Australia

The very first AFS™ Acoustic Force Spectroscopy-system in Australia has been successfully installed in the lab of Prof. Boris Martinac at the Victor Chang Cardiac Research Institute. Prof. Martinac and his team conduct research on cellular transduction processes associated with mechanosensitive ion channels. Although it has been shown that dysfunction of these ion channels contributes…
j.yeh
12 March 2019
Blog posts

New insights into Cas9 off-target activity

The paper “DNA stretching induces Cas9 off-target binding and cleavage” was just published in Nature Structural and Molecular Biology. Congratulations to all the authors! In this paper, scientists at the MRC London Institute of Medical Sciences and AstraZeneca studied how CRISPR-Cas9 differentiates between on-targets and off-targets. They used the C-Trap®…
j.yeh
8 March 2019
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