hallo
Uncategorised

Exploring mitochondrial translation processes with the C-Trap®

This month, we find the C-Trap®  featured in Nature Communications in an article published by the lab of Dr. Joanna Rorbach in which they describe mitochondrial translation initiation. The study provides insight into a relatively unexplored, yet exciting field that investigates the properties of mitochondrial ribosomes (mitoribosomes) during translation. Understanding…
Santiago Gisler
25 June 2020
Uncategorised

Single-molecule measurements with AFS® and optical tweezers reveal progressive assembly of viruses

The research lab of Dr. Gijs Wuite in the Netherlands recently published a single-molecule study in Science Advances, demonstrating the progressive self-assembly steps of viruses. Methods, such as optical tweezers and acoustic force spectroscopy (AFS®), enabled the researchers to study the transient and otherwise hard-to-verify steps associated with viral assembly.…
Santiago Gisler
14 May 2020
Dutch Tech Heroes Fighting COVID-19 | LUMICKSUncategorised

LUMICKS featured in Dutch Tech Heroes Fighting COVID-19

LUMICKS has been featured as one of the 150+ companies in the overview of Dutch Tech Heroes Fighting COVID-19 published by Techleap.nl. The Dutch non-profit organization states: In the current crisis, the Netherlands is increasingly dependent on digital and technological solutions from startups and scale-ups. It is, therefore, more important than ever that…
Doenja Jansen
8 May 2020
Uncategorised

New insights into the initiation of nucleotide excision repair found using C-Trap®

A recent publication in PNAS shows how the catalytically inactive alkyltransferase-like protein (ATL) scans and recognizes detrimental DNA alkylation lesions. The C-Trap® with correlated optical tweezers and confocal microscopy enabled researchers to investigate how ATL interacts with DNA to identify alkyl lesions and interact with associated repair proteins. The findings…
Santiago Gisler
30 April 2020
Uncategorised

Controlled ligand gradient through C-Trap® facilitates DSM measurements

A publication in the journal Micromachines describes how researchers managed to control the concentrations of DNA-binding dyes in single-molecule optical tweezers experiments on DNA. They established a controlled concentration gradient with the multi-channel laminar microfluidics system integrated with their C-Trap® correlated optical tweezers and confocal microscopy. The study demonstrates a…
Santiago Gisler
19 March 2020
Newsletter pop up