Distal bridging between nucleosomes by polycomb complex PRC2 identified with the C-Trap®

A recent study published in PNAS used single-molecule force spectroscopy to examine unknown interaction mechanisms between polycomb repressive complex 2 (PRC2) and chromatin. The authors evaluated arrays of multiple nucleosomes using their C-Trap® optical tweezers system and identified distal nucleosome bridging by PRC2. The findings provide a better understanding of…
Santiago Gisler
3 December 2020
C-Trap® installed at Emory University in AtlantaUncategorised

C-Trap® installed at Emory University in Atlanta

We are happy to announce the installation of a new C-Trap® system with correlated optical tweezers and three-color confocal imaging functionality at Emory University in Atlanta, Georgia. The installed instrument, which is managed by the research group of Prof. Laura Finzi and Dr. David Dunlap, will be used by several…
Santiago Gisler
18 November 2020

New study highlights interconvertible RecA–ssDNA states with the help of u-Flux™ microfluidics

A recent publication in FEBS Letters describes how the presence of ADP and ATP affects the structural transitions that single-stranded DNA (ssDNA) undergoes upon RecA-filament assembly. The researchers used the u-Flux™ Laminar Flow Microfluidics combined with optical tweezers to demonstrate that the bacterial homologous recombination-enzyme exists in two interconvertible states.…
Santiago Gisler
29 October 2020
LinkedIn Top Startups 2020Uncategorised

LUMICKS featured in LinkedIn Top Start-ups 2020

LUMICKS reached the 6th position in the list LinkedIn Top Start-ups 2020 in the Netherlands. We're extremely proud to be among the most resilient companies during these changing times. The LinkedIn editors define start-ups as privately held companies, that are no more than seven years old, employ over 50 people, and…
Doenja Jansen
22 September 2020

Researchers investigate the effects of biomolecular droplet structure on fusion times using the C-Trap®

In a recent publication, researchers at the University of Illinois at Chicago used the C-Trap® to study the relationship between structural properties of biomolecular condensates and their fusion times. They found that fusion times, an indicator of condensate density, varies depending on their structural organization. The findings highlight how physical…
Santiago Gisler
27 August 2020

Electrostatic effects on vimentin stiffness demonstrated with the C-Trap®

A recently published study from the lab of Prof. Sarah Köster at the University of Göttingen investigated how electrostatic conditions influence the mechanical properties of intermediate filament vimentin, such as structural stability. The researchers assessed these features by stretching the protein in different buffer conditions, using the C-Trap® with correlated optical…
Santiago Gisler
6 August 2020
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