C-Trap® installed at the National Center for Biotechnology in Madrid

We are happy to announce the installation of a C-Trap® Optical Tweezers – Fluorescence and Label-free Microscopy system at the National Center for Biotechnology (CNB), Madrid, managed by the lab of Dr. Fernando Moreno-Herrero. The team will use the C-Trap configured with dual traps and correlated three-color confocal to examine a wide range of biological processes, such as RNA translation, DNA repair and organization, and lipid nanotube formation.

The lab of Dr. Moreno-Herrero has been using single-molecule techniques, such as a home-built magnetic tweezers instrument and acoustic force microscopy (AFM) to study DNA–protein interactions. However, they found the fluorescence capabilities of the C-Trap to be an excellent complement to their extensive repertoire of methods and the best way to combine optical tweezers with confocal microscopy.

“With the C-Trap, our group can expand our capabilities to investigate nucleic acids mechanics and DNA-protein interactions in novel ways,” Dr. Moreno-Herrero explained. “We can now locate fluorescently-labeled proteins on DNA substrates and follow their dynamics in real time.”

Apart from the Moreno-Herrero lab, the research group of Dr. Borja Ibarra at the IMDEA Nanoscience Institute plans to use the installed C-Trap regularly for their research on molecular motors.

We wish Dr. Moreno-Herrero and his team good luck with their ongoing research and are excited about their upcoming results!

Do you want to discuss the applications and benefits of our C-Trap® instruments for your research? Meet our application scientists at one of the conferences we are attending, or contact us for a demo, brochures, or a quote.

Doenja Jansen

Doenja Jansen

12 October 2020

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