Dynamic single-molecule analysis offers invaluable insights into DNA repair mechanisms: HELQ in DSB case study
DNA repair is a highly complex and dynamic process that involves the interplay of numerous different proteins and components. The helicase HELQ is known to play a role in double-stranded breaks (DSBs) repair, but its molecular mechanisms remain unknown.
A study by the research group led by Simon Boulton presented how dynamic single molecule analysis leads to direct visualization of the mechanism of HELQ in DNA double-stranded breaks (DSBs) repair. Check out this application note to learn more.
